Triamterene hydrochlorothiazide

It is a single medication containing two triamterene drugs, triamterene hydrochlorothiazide and triamterene hydrochlorothiazide. From Heart Health Resources Featured Centers Health Solutions From Our Sponsors Report Problems to the triamterene Food and triamterene Drug Administration You are hydrochlorothiazide encouraged to report negative side effects of hydrochlorothiazide side effects triamterene prescription drugs to the FDA. Metabolic or triamterene Respiratory Acidosis Potassium-sparing therapy should also be avoided in severely hydrochlorothiazide ill patients in whom respiratory or metabolic acidosis may occur. Do not share your drugs with others and do not take anyone else's drugs. Triamterene hydrochlorothiazide and hydrochlorothiazide combines triamterene, a potassium-conserving diuretic, triamterene with the natriuretic agent, hydrochlorothiazide. If hyperkalemia is suspected, (warning signs include hydrochlorothiazide paresthesias, muscular weakness, fatigue, flaccid paralysis of hydrochlorothiazide the extremities, bradycardia and shock) an electrocardiogram (ECG) should be obtained. In actual salt depletion, appropriate replacement is the therapy of choice. It is a combination of two different diuretics. To lower the chance of feeling dizzy or passing out, rise slowly if you hydrochlorothiazide have hydrochlorothiazide been triamterene sitting or lying down. Potassium supplementation should not be used with dyazide (hydrochlorothiazide and triamterene) hydrochlorothiazide except in severe cases of hypokalemia. Carefully evaluate the electrolyte pattern and fluid balance. Renal : Acute renal failure (one case of irreversible renal failure has been reported interstitial nephritis, renal stones composed primarily of triamterene, elevated BUN, and serum creatinine, abnormal triamterene urinary sediment. Treatment is symptomatic and supportive. Use sunscreen and wear protective clothing when outdoors. Lithium : Lithium generally should not be given with diuretics because they reduce triamterene its renal clearance and increase the risk of lithium toxicity. Overdosing with hydrochlorothiazide has been associated with hypokalemia, hypochloremia, hydrochlorothiazide hyponatremia, dehydration, lethargy triamterene (may progress to coma) and gastrointestinal irritation. Triamterene is primarily metabolized to the sulfate conjugate of hydroxytriamterene. Report prolonged diarrhea or vomiting to your doctor. Read circulars for hydrochlorothiazide lithium preparations before use of such concomitant therapy with dyazide (hydrochlorothiazide and triamterene). Tell your doctor hydrochlorothiazide if you have too much sweat, fluid loss, throwing up, or loose stools. The dosages range from.5 to 75 mg ( triamterene ) and 25 to 50 mg ( hydrochlorothiazide ). The triamterene and hydrochlorothiazide components of this product are well absorbed and are bioequivalent to liquid preparations of the individual components administered orally. Fluid and electrolyte imbalances are the most important concern. Your hydrochlorothiazide doctor will prescribe the appropriate dosage depending on hydrochlorothiazide your condition and response to the medication. Parathyroid Function : Thiazides should be discontinued before carrying out tests triamterene for parathyroid function. Respiratory : Allergic pneumonitis, pulmonary edema, respiratory distress. All patients changed from less bioavailable formulations of triamterene and hydrochlorothiazide to this tablet formulation should be monitored clinically and for serum potassium after the transfer. Hydrochlorothiazide is slightly soluble in water and freely soluble in sodium hydroxide solution, n-butylamine and dimethylformamide. Tell your doctor right away if you get any hydrochlorothiazide new or worse signs. If you have diabetes, this product may affect your blood sugar. This medicine may raise blood sugar. Tell your doctor if you have kidney disease or diabetes. The FDA approved in December 1965. Keep hydrochlorothiazide all drugs in a safe place. Impairment of Fertility : Studies of the effects of dyazide (hydrochlorothiazide and triamterene) hydrochlorothiazide (the combination or of triamterene alone on animal reproductive function have not been conducted. Warnings warnings Hyperkalemia Abnormal elevation of serum potassium levels (greater than or equal.5 mEq/liter) can occur with all potassium-sparing diuretic combinations, including dyazide (hydrochlorothiazide and triamterene). Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. On a body-weight basis, these triamterene doses are 600 times (in mice) and 100 times (in rats) the Maximum Recommended Human Dose triamterene (mrhd) for the hydrochlorothiazide component of dyazide (hydrochlorothiazide and triamterene) at 50 mg/day (or.0 mg/kg/day based on 50 kg individuals). The chance is greatest in people with high blood sugar (diabetes kidney disease, very bad illness, and/or in older adults. If dyazide (hydrochlorothiazide and triamterene) is employed, frequent evaluations of acid/base balance and serum electrolytes are necessary. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Onset of hydrochlorothiazide's diuretic effect occurs within 2 hours and the peak action takes place in 4 hours. What are some things I need to know or do while I take Hydrochlorothiazide and Triamterene? If you have questions about triamterene side effects, call your doctor. Especially tell your doctor if you: have a history of kidney, liver, heart, or parathyroid disease have diabetes have high potassium levels have a history of kidney stones, gout, or lupus hydrochlorothiazide are allergic to triamterene or hydrochlorothiazide have a history. To keep from having sleep problems, try to take before. Precautions, Drug Interactions ). Warning/caution: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Dyazide (hydrochlorothiazide and triamterene) should be used with caution in patients with a history of renal stones. Talk with your doctor. Hyperkalemia has been reported in diabetic patients with the use of potassium-conserving agents even in the absence of apparent renal impairment. Drug interactions Angiotensin-converting Enzyme Inhibitors : Potassium-sparing agents should be used with caution in conjunction with angiotensin-converting enzyme (ACE) inhibitors due to an increased risk of hyperkalemia. Since uncorrected hyperkalemia may be fatal, serum potassium levels must be monitored at frequent intervals especially in patients first receiving triamterene and hydrochlorothiazide capsules, when dosages are changed or with any illness that may influence triamterene renal function). Clinical experience with the administration of two.5 mg/25 mg tablets hydrochlorothiazide daily in divided doses (rather than as a single dose) triamterene hydrochlorothiazide suggests an increased risk of electrolyte imbalance and renal dysfunction. Single daily doses.5 mg triamterene resulted lisinopril hydrochlorothiazide in greater increases in serum potassium than a lower dose (25 mg while doses greater than.5 mg of triamterene,.e., 75 mg and 100 mg, resulted in no additional elevations in serum potassium levels. This medicine may make you sunburn more easily. The common complications of hyperparathyroidism such as bone resorption and peptic ulceration have not been seen. If this edema produces discomfort, increased recumbency will often provide relief. Triamterene / hydrochlorothiazide is an oral diuretic (water pill) that is used for treating high blood pressure ( hypertension ) and edema (water accumulation). If serious hypokalemia (serum potassium less than.0 mEq/L) is demonstrated by repeat serum potassium determinations, dyazide (hydrochlorothiazide and triamterene) should be discontinued and potassium chloride hydrochlorothiazide supplementation initiated. Side effects of include abdominal pain, nausea, vomiting, rash, headache, dizziness, constipation, low blood pressure, electrolyte disturbance (for example, high potassium levels muscle cramps, hypersensitivity, pancreatitis, and jaundice. Throw away unused or expired drugs. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Limit your time in the sun. At these doses, which are multiples of the mrhd equal to 3,000 for mice and 1,000 for rats, based on body-weight, and equal to 282 hydrochlorothiazide for mice and 206 for rats, based on body-surface area, there was no evidence of harm to the fetus. If the serum potassium exceeds.5 mEq/liter more vigorous therapy is required. Excessive doses of the triamterene component may elicit hyperkalemia, dehydration, nausea, vomiting and weakness and possibly hypotension. Peak plasma levels are achieved within one lisinopril hydrochlorothiazide hour after dosing. Choose one, less than a week, a couple weeks. Symptoms include acute onset of decreased visual acuity or ocular pain and typically occur within hours to weeks of drug initiation. Ophthalmic: xanthopsia, transient blurred vision. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Triamterene and hydrochlorothiazide is also indicated for those patients who require a thiazide diuretic and in whom the development of hypokalemia cannot be risked (e.g., patients on concomitant digitalis triamterene preparations, or with a history of cardiac arryhthmias, etc.). Positive test results were obtained in the in vitro CHO Sister Chromatid Exchange (clastogenicity) test, and in the mouse Lymphoma Cell (mutagenicity) triamterene assays, using concentrations of hydrochlorothiazide of 43 to 1300 mcg/mL. Triamterene and Hydrochlorothiazide Tablets, USP,.5 mg/ 25 mg are available for oral administration as green, oval bioconvex tablets, scored and engraved.5 bisect 25 on one side, APO on the other side.

Hydrochlorothiazide 12.5 mg

80 mg25 mg W podwjnie lepym, kontrolowanym badaniu klinicznym (n687 pacjentw ocenianych pod wzgldem skutecznoci) u pacjentw nieodpowiadajcych na dawk produktu zoonego 80 mg/12,5 mg, wykazano wikszy o 2,7/1,6 mmHg (cinienie skurczowe/rozkurczowe; rnica pomidzy skorygowanymi rednimi zmianami w hydrochlorothiazide stosunku do wartoci. Hydrochlorotiazyd jest prawie cakowicie wydalany w postaci niezmienionej w moczu. 5.2 Pharmacokinetic properties Lisinopril Lisinopril is an orally active non-sulphydryl-containing ACE inhibitor. Glikozydy naparstnicy, leki przeciwarytmiczne z hydrochlorothiazide lekami mogcymi wywoa torsades de pointes (w tym niektre leki przeciwarytmiczne dla ktrych hipokaliemia jest czynnikiem predysponujcym, takimi jak: - leki przeciwarytmiczne klasy Ia (np. W odrnieniu od lekw z grupy inhibitorw konwertazy angiotensyny, sartany nie nasilaj efektw zalenych od bradykininy,. Nie naley hydrochlorothiazide stosowa hydrochlorotiazydu w samoistnym nadcinieniu ttniczym u kobiet w ciy z wyjtkiem rzadkich sytuacji, kiedy niemoliwe jest zastosowanie alternatywnego leczenia. Produkty lecznicze, ktre mog spowodowa zwikszenie stenia potasu lub wywoa hiperkaliemi (np. Cyklofosfamid, metotreksat) Tiazydy mog zmniejszy wydalanie nerkowe cytotoksycznych produktw leczniczych i nasili ich hamujce dziaanie na czynno szpiku. Jak wynika z dowiadczenia w stosowaniu innych produktw leczniczych, ktre wpywaj na ukad renina-angiotensyna, jednoczesne stosowanie powyszych produktw leczniczych moe prowadzi do zwikszenia stenia potasu w surowicy i w zwizku z tym nie jest zalecane (patrz punkt.4). 5.3 Preclinical safety hydrochlorothiazide data Lisinopril Preclinical data reveal no special hazard for humans based on conventional studies of general pharmacology, repeated dose toxicity, genotoxicity, and carcinogenic potential. The following list contains some of the key side effects that may hydrochlorothiazide occur while taking hydrochlorothiazide. Cukrzyca utajona moe si ujawni w trakcie leczenia tiazydem. W badaniach in vitro nie wykazano dziaania mutagennego telmisartanu i odpowiedniego dziaania klastogennego, nie ma rwnie hydrochlorothiazide dowodw na dziaanie rakotwrcze u szczurw i myszy. Non-depolarising muscle relaxants (e.g. Pacjenci powinni by hydrochlorothiazide odpowiednio nawodnieni, naley rwnie rozway konieczno hydrochlorothiazide monitorowania czynnoci nerek po rozpoczciu terapii towarzyszcej, a pniej okresowo. Wspczynnik ryzyka dla telmisartanu wobec ramiprylu wynosi 1,01 (97,5 CI; 0,931,10; p (rwnowano) 0,0019 z marginesem wynoszcym 1,13). Do czynnikw ryzyka rozwoju ostrej jaskry z zamknitym ktem przesczania moe nalee uczulenie na sulfonamidy lub penicylin w wywiadzie. Angiotensin Converting Enzyme Inhibitors, ACEi antagonistw receptora angiotensyny II (ang. Ontarget was a study conducted in patients with a history of cardiovascular hydrochlorothiazide or cerebrovascular disease, or type 2 diabetes mellitus accompanied by evidence of end-organ damage. Preparat moe osabi oddziaywanie amin katecholowych (np. Preclinical data is broadly consistent with clinical experience. Dwa due randomizowane, kontrolowane badania hydrochlorothiazide kliniczne ontarget (ang. If progressive renal impairment becomes evident, as indicated by rising non-protein nitrogen, careful reappraisal of therapy is necessary, with consideration given to discontinuing diuretic therapy (see section.3). Beta-blokerw, antagonistw wapnia) lub lekw mogcych obnia cinienie ttnicze (np. Jeli u pacjenta hydrochlorothiazide wtroba nie funkcjonuje waciwie, zwyka dawka nie powinna by wiksza hydrochlorothiazide ni 40 mg telmisartanu i 12,5 mg hydrochlorotiazydu na dob. Digoksyna Zaobserwowano wzrost mediany maksymalnego stenia digoksyny w osoczu (49) i stenia minimalnego (20) gdy podawano telmisartan lisinopril hydrochlorothiazide jednoczenie z digoksyn, Podczas rozpoczynania, dostosowywania dawki i koczenia leczenia telmisartanem naley monitorowa stenie digoksyny w celu utrzymania w zakresie terapeutycznym. W przypadku znacznej hiperkalcemii naley wykona badania oceniajce czynno przytarczyc. The use of potassium supplements, potassium-sparing agents or potassium-containing salt substitutes, particularly in patients with impaired renal function, may lead to a significant increase in serum potassium. Jeeli klirens kreatyniny jest mniejszy ni 30 ml/min hydrochlorothiazide preparat nie jest skuteczny. Lekarz indywidualnie ustali dawkowanie w zalenoci od stanu chorego i jego reakcji hydrochlorothiazide na leczenie. Jak przechowywa lek egis Lek naley przechowywa w miejscu niewidocznym i niedostpnym dla dzieci. Typowe objawy zaburzenia gospodarki pynowej lub elektrolitowej obejmuj sucho bony luzowej w jamie ustnej, osabienie, letarg, senno, niepokj, ble lub skurcze miniowe, nudnoci (mdoci wymioty, zmczenie mini oraz nieprawidowo przyspieszone ttno (szybciej ni 100 uderze na minut). Rzadko zanotowano przypadki z antagonistami receptora angiotensyny II (w tym Nie jest zalecane jednoczesne stosowanie litu i produktu (patrz punkt.4). If you are a breast-feeding mother hydrochlorothiazide and are taking hydrochlorothiazide, hydrochlorothiazide it may affect your baby.

Side effects of hydrochlorothiazide

The mortality rate. Fine SR, Lodha A, Zoneraich S, effects Mollura JL "Thiazide-induced pulmonary edema." Ann Pharmacother 30 (1996 416. Lowering Blood Pressure Exercise Tips Pictures Dyazide Professional Information side effects side Adverse effects are listed in side decreasing order of severity. Before using this medication, tell your hydrochlorothiazide doctor or pharmacist your medical history, especially of: diabetes, gout, kidney disease, liver hydrochlorothiazide disease, lupus. You may need to show airport staff the pharmacy label for your medication. Grunwald MH, Halevy S, Livni E "Allergic vasculitis induced by hydrochlorothiazide: confirmation by mast cell degranulation test." Isr J Med Sci 25 (1989 572-4. Refills A prescription for this medication effects is refillable. This means your child may need to take this drug every other day or for three to five days each week. The use of Hydrochlorothiazide may change magnesium levels. Musculoskeletal : Muscle cramps. You can also check your blood pressure at home. The use of this medicine may change sodium levels. These problems often effects occur within hours to weeks after starting this medication. A replacement therapy is chosen in case of actual salt depletion. Chronic conditions like high cholesterol, diabetes, gout, and asthma may worsen with high doses. Robinson HN, Morison WL, Hood AF "Thiazide diuretic effects therapy and chronic photosensitivity." Arch Dermatol 121 side (1985 522-4. Ask your doctor about foods high in potassium (such as bananas, orange juice) or about using a effects salt substitute containing potassium. SingleCare, a leading online service for prescription, dental, and vision discounts, has partnered with most major pharmacies around the country to help you save up to 80 percent off prescription costs. Dyazide Consumer Information, get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling side of your face, side lips, tongue, or throat. These include: the type and severity of the condition youre using hydrochlorothiazide to treat your age the form effects of hydrochlorothiazide you take other medical conditions you may have, such effects as kidney damage Typically, your doctor will. In these studies, side effects are documented and compared to side effects that occur in a similar group of people not taking the medicine. Sensitivity to the sun, muscle spasm, pancreatitis side (inflammation of the pancreas ). However, not everyone who takes the medicine will experience side effects. Thiazide-type diuretics like hydrochlorothiazide can also elevate blood sugar. Dietz MW "Iatrogenic jejunal ulcer." Am J Roentgenol Radium Ther Nucl Med 99 (1967 136-8. Hyperuricamia may be an important side consideration in patients with a history of gout. Hypersensitivity : Anaphylaxis, rash, urticaria, subacute cutaneous lupus erythematosus-like reactions, photosensitivity. How it works, hydrochlorothiazide belongs to a class of drugs called thiazide diuretics.

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